IIT Roorkee researchers identify the role of white blood cell markers in sepsis-related complications

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ROORKEE: Researchers at the Indian Institute of Technology Roorkee, led by Prof. Pranita P Sarangi, Department of Biosciences and Bioengineering, IIT Roorkee, have shown the role of specific immune cell markers on the outcomes of severe infection and sepsis. This study, funded by the BioCARe Women Scientist grant and Innovative Young Biotechnologist Award grant from the Department of Biotechnology, GoI, has provided important insights into the role of immune cell markers on sepsis-related complications.

Neutrophils, monocytes and macrophages are white blood cells that act as scavengers of dead cells and foreign bodies such as bacteria and other pathogens. They move from the blood to the site of an infection to mop up the disease-causing foreign matter. However, in uncontrolled and severe infection, commonly called ‘sepsis’, there is abnormal activation and localization of these…

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